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Article

[The spontaneous YMDD mutation rate in chronic hepatitis B patients].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Dec 2009

Min Xiao-chun, Miao Xiao-hui, Zhao Shu-min, Zhao Ke-kai, Yang De-gang

Abstract excerpt

OBJECTIVE: To investigate the spontaneous YMDD mutation rate. METHODS: Serum samples collected from 196 untreated chronic HBV patients were detected by primer-specific real-time PCR. RESULTS: Among 196 patients, spontaneous YMDD variants were detected in 21 subjects (20 YVDD mutants and 1 YIDD mutant). YMDD variants account for more than 50%, 25% to 50%, 9% to 25% of total virus load in 1, 5 and 15 patients,...

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Identifiers

PMID: 20038327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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