Article
YMDD mutations in patients with chronic hepatitis B untreated with antiviral medicines.
World journal of gastroenterology - 14 Feb 2005
Huang Zhong-Min, Huang Qi-Wen, Qin Ya-Qin, He Yan-Zhuan, Qin Hou-Ji, Zhou Yiao-Nan, Xu Xiang, Huang Mei-Jin
Abstract excerpt
AIM: To polymerase P region (YMDD) mutations of hepatitis B virus gene (HBV DNA) in patients with chronic hepatitis B (CHB) untreated with antiviral medicines and to explore its correlation with pre-c-zone mutations, HBV genotypes and HBV DNA level, and to observe its curative effect. METHODS: A total of 104 cases (38 cases in group of familial aggregation and 66 cases in group of non-familial aggregation) were...
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