Article
ACE I/D genotype-related increase in ACE plasma activity is a better predictor for schizophrenia diagnosis than the genotype alone.
Schizophrenia research - 1 May 2015
Gadelha Ary, Yonamine Camila M, Ota Vanessa K, Oliveira Vitor, Sato João Ricardo, Belangero Sintia I, Bressan Rodrigo A, Hayashi Mirian A F
Abstract excerpt
BACKGROUND: Angiotensin-I converting enzyme (ACE) is a key component of the renin-angiotensin system (RAS). Although the several contradictory data, ACE has been associated with schizophrenia (SCZ) pathophysiology. Here the ACE activity of SCZ patients and healthy controls (HCs), and its possible correlations with the ACE polymorphism genotype and symptomatic dimensions, was investigated. METHODOLOGY: ACE...
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