Article
Cytomegalovirus glycoprotein H genotype distribution and the relationship with hearing loss in children.
Journal of medical virology - 1 Aug 2014
Paradowska Edyta, Jabłońska Agnieszka, Studzińska Mirosława, Kasztelewicz Beata, Zawilińska Barbara, Wiśniewska-Ligier Małgorzata, Dzierżanowska-Fangrat Katarzyna, Woźniakowska-Gęsicka Teresa, Kosz-Vnenchak Magdalena, Leśnikowski Zbigniew J
Abstract excerpt
Cytomegalovirus (CMV) is a leading cause of congenital infection and a leading infectious cause of hearing loss in children. The ORF UL75 gene encodes envelope glycoprotein H (gH), which is essential for CMV entry into host cells and the target of the immune response in humans. However, the distribution of gH variants and the relationship between the viral genotype, viral load, and sequelae in children infected...
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