Article
Association of CMV genomic mutations with symptomatic infection and hearing loss in congenital CMV infection.
BMC infectious diseases - 10 Dec 2019
Dobbins G Clement, Patki Amit, Chen Dongquan, Tiwari Hemant K, Hendrickson Curtis, Britt William J, Fowler Karen, Chen Jake Y, Boppana Suresh B, Ross Shannon A
Abstract excerpt
BACKGROUND: Congenital cytomegalovirus (cCMV) infection is the most common congenital infection and a leading cause of long-term neurological and sensory sequelae, the most common being sensorineural hearing loss (SNHL). Despite extensive research, clinical or laboratory markers to identify CMV infected children with increased risk for disease have not been identified. This study utilizes viral whole-genome next...
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