Article
Genotypic diversity and mixed infection in newborn disease and hearing loss in congenital cytomegalovirus infection.
The Pediatric infectious disease journal - 1 Oct 2013
Pati Sunil K, Pinninti Swetha, Novak Zdenek, Chowdhury Nazma, Patro Raj K, Fowler Karen, Ross Shannon, Boppana Suresh
Abstract excerpt
BACKGROUND: Congenital cytomegalovirus (cCMV) is a common congenital infection and a leading nongenetic cause of sensorineural hearing loss (SNHL). CMV exhibits extensive genetic variability, and infection with multiple CMV strains (mixed infection) was shown to be common in congenital CMV. The role of mixed infections in disease and outcome remains to be defined. METHODS: Genotyping of envelope glycoproteins,...
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