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Article

Genetic variations in the gB, UL144 and UL149 genes of human cytomegalovirus strains collected from congenitally and postnatally infected Japanese children.

Archives of virology - 1 Jan 2008

Yan Hainian, Koyano Shin, Inami Yuhki, Yamamoto Yumiko, Suzutani Tatsuo, Mizuguchi Masashi, Ushijima Hiroshi, Kurane Ichiro, Inoue Naoki

Abstract excerpt

Human cytomegalovirus (CMV) is the leading cause of intrauterine viral infection. The association of genetic polymorphisms in some particular genes with the incidence and severity of congenital infection has been controversial. To address this issue, we analyzed the genotypes of the glycoprotein B (gB), UL144 and UL149 genes of CMV clinical strains obtained from 33 congenitally and 31 postnatally infected...

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PMID: 18273679
DOI: 10.1007/s00705-008-0044-7

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