Article
Human cytomegalovirus UL55, UL144, and US28 genotype distribution in infants infected congenitally or postnatally.
Journal of medical virology - 1 Oct 2015
Paradowska Edyta, Studzińska Mirosława, Suski Patrycja, Kasztelewicz Beata, Wiśniewska-Ligier Małgorzata, Zawilińska Barbara, Gaj Zuzanna, Nowakowska Dorota
Abstract excerpt
Cytomegalovirus (CMV) is the most common cause of congenital infection. This pathogen exhibits extensive genetic variability in the genes that encode structural envelope glycoproteins, regulatory proteins, and proteins that contribute to immune evasion. However, the role of specific viral strains in the outcome of congenital CMV infection is unclear. Variation in the UL55 gene encoding glycoprotein B (gB), the...
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