Article
A transcription network of interlocking positive feedback loops maintains intracellular iron balance in archaea.
Nucleic acids research - 29 Sept 2017
Martinez-Pastor Mar, Lancaster W Andrew, Tonner Peter D, Adams Michael W W, Schmid Amy K
Abstract excerpt
Iron is required for key metabolic processes but is toxic in excess. This circumstance forces organisms across the tree of life to tightly regulate iron homeostasis. In hypersaline lakes dominated by archaeal species, iron levels are extremely low and subject to environmental change; however, mechanisms regulating iron homeostasis in archaea remain unclear. In previous work, we demonstrated that two transcription...
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