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Article

Wnt-Dependent T-Cell Factor-4 Controls Human Etravillous Trophoblast Motility

10 Mar 2014

Abstract excerpt

Formation of migratory extravillous trophoblasts (EVTs) is critical for human placentation and hence embryonic development. However, key regulatory growth factors, hormones, and nuclear proteins controlling the particular differentiation process remain poorly understood. Here, the role of the Wingless (Wnt)-dependent transcription factor T-cell factor-4 (TCF-4) in proliferation and motility was investigated using...

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PMID: 24605829
DOI: 10.1210/en.2013-2042

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