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Article

Structure, mechanism, and enantioselectivity shifting of lipase LipK107 with a simple way.

Biochimica et biophysica acta - 1 Jul 2014

Zhang Lujia, Gao Bei, Yuan Zuanning, He Xiao, Yuan Y Adam, Zhang John Z H, Wei Dongzhi

Abstract excerpt

Because of the complex mechanisms of enzymatic reactions, no precise and simple method of understanding and controlling the chiral selectivity of enzymes has been developed. However, structure-based rational design is a powerful approach to engineering enzymes with desired catalytic activities. In this work, a simple, structure-based, large-scale in silico design and virtual screening strategy was developed and...

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Identifiers

PMID: 24602769
DOI: 10.1016/j.bbapap.2014.02.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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