Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Nexus of Prematurity, Birth Defects, and Intrauterine Growth Restriction: A Role for Plac1-Regulated Pathways

1 Jan 2014

Abstract excerpt

Epidemiological studies have demonstrated an increased prevalence of birth defects and intrauterine growth restriction (IUGR) among infants born prematurely suggesting they share common biological determinants. The identification of key regulatory pathways contributing to this nexus is essential to ongoing efforts to develop effective intervention strategies. Plac1 is a paternally imprinted and X-linked gene that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital Anomalies and Fetal Surgery
Share to Genetic Syndromes and Imprinting
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24600606
DOI: 10.3389/fped.2014.00008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Nexus of Prematurity, Birth Defects, and Intrauterine Growth Restriction: A Role for Plac1-Regulated PathwaysPMID 24600606Read ↗

Plac1 (placenta-specific 1) is widely expressed during fetal development and is associated with a lethal form of hydrocephalus.Semantic proximity Read ↗

Plac1 (placenta-specific 1) is essential for normal placental and embryonic development.Semantic proximity Read ↗

Transcriptomic Analysis of <i>Plac1</i> Ablation Reveals Broad Alterations in Signaling Pathways Essential for Prenatal Development and Overlap with a Preeclampsia-Associated SignatureSemantic proximity Read ↗

PLAC1, an Xq26 Gene with Placenta-Specific ExpressionSemantic proximity Read ↗

Genetic and epigenetic mechanisms of preterm birth: Advancing from multi-omics insights to precision prevention and clinical managementSemantic proximity Read ↗

Genetic aspects of birth defects: new understandings of old problems.Semantic proximity Read ↗

Lentiviral Vector-Mediated Complementation Restored Fetal Viability but Not Placental Hyperplasia in Plac1-Deficient Mice1Semantic proximity Read ↗

The search for genetic determinants of human neural tube defects.Semantic proximity Read ↗

Importance of gene-environment interactions in the etiology of selected birth defects.Semantic proximity Read ↗

Inborn errors of development: disruption of pathways critical for normal development.Semantic proximity Read ↗

Birth defects associated with perturbations in preimplantation, gastrulation, and axis extension: from conjoined twinning to caudal dysgenesisSemantic proximity Read ↗

Regulation of Placental Development and Its Impact on Fetal Growth—New Insights From Mouse ModelsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.