Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plac1 (placenta-specific 1) is widely expressed during fetal development and is associated with a lethal form of hydrocephalus.

Birth defects research. Part A, Clinical and molecular teratology - 1 Sept 2013

Kong Xiaoyuan, Jackman Suzanne M, Fant Michael E

Abstract excerpt

BACKGROUND: Plac1 is an X-linked gene essential for normal placental development. Plac1 ablation is associated with placentomegaly and intrauterine growth retardation. Additionally, Plac1-null mice exhibit reduced postnatal viability. This study was conducted as part of our ongoing examination of the postnatal phenotype associated with Plac1 ablation. METHODS: Plac1 was deleted in murine embryonic stem cells and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Galactosidase
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hydrocephalus

Share to Immunohistochemistry

Share to In Situ Hybridization

Share to Mice, Knockout

Share to Pregnancy Proteins

Share to Real-Time Polymerase Chain Reaction

Source

Identifiers

PMID: 24014101
DOI: 10.1002/bdra.23171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plac1 (placenta-specific 1) is widely expressed during fetal development and is associated with a lethal form of hydrocephalus.PMID 24014101Read ↗

Plac1 (placenta-specific 1) is essential for normal placental and embryonic development.Semantic proximity Read ↗

The Nexus of Prematurity, Birth Defects, and Intrauterine Growth Restriction: A Role for Plac1-Regulated PathwaysSemantic proximity Read ↗

Transcriptomic Analysis of <i>Plac1</i> Ablation Reveals Broad Alterations in Signaling Pathways Essential for Prenatal Development and Overlap with a Preeclampsia-Associated SignatureSemantic proximity Read ↗

Lentiviral Vector-Mediated Complementation Restored Fetal Viability but Not Placental Hyperplasia in Plac1-Deficient Mice1Semantic proximity Read ↗

PLAC1, an Xq26 Gene with Placenta-Specific ExpressionSemantic proximity Read ↗

Placentation defects are highly prevalent in embryonic lethal mouse mutants.Semantic proximity Read ↗

A Placenta-Specific Gene Ectopically Activated in Many Human Cancers Is Essentially Involved in Malignant Cell ProcessesSemantic proximity Read ↗

<i>Cited1</i> Is Required in Trophoblasts for Placental Development and for Embryo Growth and SurvivalSemantic proximity Read ↗

Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth.Semantic proximity Read ↗

PIEZO1 mutation: a rare aetiology for fetal ascites.Semantic proximity Read ↗

A novel nonsense mutation in the L1CAM gene responsible for X-linked congenital hydrocephalus.Semantic proximity Read ↗

STOX1 deficiency is associated with renin-mediated gestational hypertension and placental defectsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.