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Article

Transcriptome profiling as a biological marker for bipolar disorder sub-phenotypes.

Advances in medical sciences - 1 Mar 2024

Pawlak Joanna, Szczepankiewicz Aleksandra, Skibińska Maria, Narożna Beata, Kapelski Paweł, Zakowicz Przemysław, Gattner Karolina, Spałek Dominik, Mech Łukasz, Dmitrzak-Węglarz Monika

Abstract excerpt

PURPOSE: Bipolar affective disorder (BP) causes major functional impairment and reduced quality of life not only for patients, but also for many close relatives. We aimed to investigate mRNA levels in BP patients to find differentially expressed genes linked to specific clinical course variants; assuming that several gene expression alterations might indicate vulnerability pathways for specific course and...

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PMID: 38368745
DOI: 10.1016/j.advms.2024.02.002

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