Article
Amyloid A amyloidosis in a Japanese patient with familial Mediterranean fever associated with homozygosity for the pyrin variant M694I/M694I.
Modern rheumatology - 1 Mar 2014
Nakamura Tadashi, Migita Kiyoshi, Ando Yukio, Takaoka Hirokazu, Suzushima Hitoshi, Shiraishi Naoki
Abstract excerpt
Familial Mediterranean fever (FMF) is an autoinflammatory disease common in eastern Mediterranean populations. The most severe complication is the development of secondary amyloid A (AA) amyloidosis. A 51-year-old Japanese male who had been suffering from periodic fever since in his twenties was referred to our hospital for proteinuria. Histological findings from renal biopsy revealed the deposition of AA amyloid...
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