Article
The M694I/M694I genotype: A genetic risk factor of AA-amyloidosis in a group of Algerian patients with familial Mediterranean fever.
European journal of medical genetics - 1 Mar 2017
Ait-Idir Djouher, Djerdjouri Bahia, Bouldjennet Faiza, Taha Rowaida Z, El-Shanti Hatem, Sari-Hamidou Rawda, Khellaf Ghalia, Benmansour Mustapha, Benabadji Mohamed, Haddoum Farid
Abstract excerpt
Familial Mediterranean fever (FMF, OMIM 249100) is the most common hereditary fever, resulting from mutations in MEFV. FMF is characterized by episodic febrile attacks and polyserositis. Renal AA-amyloidosis is a major complication, which often leads to end-stage renal disease in untreated patients. The data about the renal AA-amyloidosis secondary to FMF are scarce in North African countries and non-existent in...
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