Predictors of AA amyloidosis in familial Mediterranean fever.

doi:10.1007/s00296-014-3205-x

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Article

Predictors of AA amyloidosis in familial Mediterranean fever.

Rheumatology international - 1 Jul 2015

Mukhin Nikolay A, Kozlovskaya Lidiya V, Bogdanova Marina V, Rameev Vilen V, Moiseev Sergey V, Simonyan Armine Kh

Abstract excerpt

The aim of the study was to evaluate the clinical and genetic predictors of AA amyloidosis in patients with familial Mediterranean fever (FMF). We retrospectively studied 170 Armenian patients who were admitted to the two tertiary centers in 2003-2014. The diagnosis of amyloidosis that was suspected clinically (new proteinuria or nephrotic syndrome) was confirmed histologically. Screening for MEFV gene mutations...

Topics

Adult
Amyloidosis
Armenia
Chi-Square Distribution
Cytoskeletal Proteins
DNA Mutational Analysis
Familial Mediterranean Fever
Female
Genetic Markers
Genetic Predisposition to Disease
Heterozygote
Homozygote
Humans
Male
Mutation
Odds Ratio
Phenotype
Prognosis

Source

Open in PubMed

Identifiers

PMID: 25586652
DOI: 10.1007/s00296-014-3205-x

Genes

MEFV

Variants

Provenance

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