Article
Clinical characteristics of 15 children with juvenile myelomonocytic leukaemia who developed blast crisis: MDS Committee of Japanese Society of Paediatric Haematology/Oncology.
British journal of haematology - 1 Jun 2014
Honda Yuko, Tsuchida Masahiro, Zaike Yuji, Masunaga Atsuko, Yoshimi Ayami, Kojima Seiji, Ito Masafumi, Kikuchi Akira, Nakahata Tatsutoshi, Manabe Atsushi
Abstract excerpt
Juvenile myelomonocytic leukaemia (JMML) is a rare haematopoietic stem cell disease of early childhood, which can progress to blast crisis in some children. A total of 153 children diagnosed with JMML were reported to the Myelodysplastic Syndrome Committee in Japan between 1989 and 2007; 15 of them (9·8%) had 20% or more blasts in the bone marrow (blast crisis) during the disease course. Blast crisis occurred...
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