Article
Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia: molecular classification and treatment options.
British journal of haematology - 1 Mar 2008
Niemeyer Charlotte Marie, Kratz Christian Peter
Abstract excerpt
Myelodysplastic syndromes (MDS) and the mixed myelodysplastic/myeloproliferative disorder juvenile myelomonocytic leukaemia (JMML) are rare haematopoietic stem cell diseases in children. While MDS-initiating events remain largely obscure, a growing body of clinical, genetic and laboratory evidence suggests that JMML is, at least in part, caused by aberrant signal transduction resulting from mutations of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
