Article
Induction of Type I Interferon Signaling Determines the Relative Pathogenicity of Staphylococcus aureus Strains
20 Feb 2014
Abstract excerpt
The tremendous success of S. aureus as a human pathogen has been explained primarily by its array of virulence factors that enable the organism to evade host immunity. Perhaps equally important, but less well understood, is the importance of the intensity of the host response in determining the extent of pathology induced by S. aureus infection, particularly in the pathogenesis of pneumonia. We compared the...
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