Article
The Role of Innate Immunity in Promoting SaeR/S-Mediated Virulence in Staphylococcus aureus
29 Jun 2013
Abstract excerpt
The ability of Staphylococcus aureus to infect tissues is dependent on precise control of virulence through gene-regulatory systems. While the SaeR/S two-component system has been shown to be a major regulator of S. aureus virulence, the influence of the host environment on SaeR/S-regulated genes (saeR/S targets) remains incompletely defined. Using QuantiGene 2.0 transcriptional assays, we examined expression of...
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