Cigarette Smoke Extract–Exposed Methicillin-Resistant <i>Staphylococcus aureus</i> Regulates Leukocyte Function for Pulmonary Persistence

doi:10.1165/rcmb.2015-0397oc

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Cigarette Smoke Extract–Exposed Methicillin-Resistant <i>Staphylococcus aureus</i> Regulates Leukocyte Function for Pulmonary Persistence

2 Jun 2016

Abstract excerpt

Cigarette smoke (CS) predisposes exposed individuals to respiratory infections not only by suppressing immune response but also by enhancing the virulence of pathogenic bacteria. As per our observations, in methicillin-resistant Staphylococcus aureus strain USA300, CS extract (CSE) potentiates biofilm formation via the down-regulation of quorum-sensing regulon accessory gene regulator. Because accessory gene...

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PMID: 27253086
DOI: 10.1165/rcmb.2015-0397oc

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