Article
Amino acid sequence analysis in patients with chronic HCV genotype 1b infection during pegylated interferon-α2a and ribavirin therapy.
Antiviral therapy - 1 Jan 2014
Fu Juan-Juan, Kong Wei-Jing, Jiang Dong, Pan Xiu-Cheng, Wei Lai
Abstract excerpt
BACKGROUND: Amino acid variations in several HCV genomic regions have been reported to be associated with response to interferon (IFN)-α plus ribavirin (RBV) combination therapy. However, the results remain controversial. In this study, we further investigated the amino acid variation of full-length HCV genome and its correlation to the response to pegylated interferon (PEG-IFN)-α2a and RBV combination therapy in...
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