Article
Genome-wide analysis of single nucleotide polymorphisms and copy number variants in fibromyalgia suggest a role for the central nervous system.
Pain - 1 Jun 2014
Docampo Elisa, Escaramís Georgia, Gratacòs Mònica, Villatoro Sergi, Puig Anna, Kogevinas Manolis, Collado Antonio, Carbonell Jordi, Rivera Javier, Vidal Javier, Alegre Jose, Estivill Xavier, Rabionet Raquel
Abstract excerpt
Fibromyalgia (FM) is a highly disabling syndrome defined by a low pain threshold and a permanent state of pain. The mechanisms explaining this complex disorder remain unclear, and its genetic factors have not yet been identified. With the aim of elucidating FM genetic susceptibility factors, we selected 313 FM cases having low comorbidities, and we genotyped them on the Illumina 1 million duo array. Genotypic...
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