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Article

Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia.

Arthritis and rheumatism - 1 Feb 2012

Smith Shad B, Maixner Dylan W, Fillingim Roger B, Slade Gary, Gracely Richard H, Ambrose Kirsten, Zaykin Dmitri V, Hyde Craig, John Sally, Tan Keith, Maixner William, Diatchenko Luda

Abstract excerpt

OBJECTIVE: Fibromyalgia (FM) represents a complex disorder that is characterized by widespread pain and tenderness and is frequently accompanied by additional somatic and cognitive/affective symptoms. Genetic risk factors are known to contribute to the etiology of the syndrome. The aim of this study was to examine >350 genes for association with FM, using a large-scale candidate gene approach. METHODS: The study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21905019
DOI: 10.1002/art.33338
PMCID: PMC3237946

Genes

TAAR1
CNR1
GABRB3
GBP1
GRIA4
RGS4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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