Article
Discovery of potential new gene variants and inflammatory cytokine associations with fibromyalgia syndrome by whole exome sequencing.
PloS one - 1 Jan 2013
Feng Jinong, Zhang Zhifang, Wu Xiwei, Mao Allen, Chang Frances, Deng Xutao, Gao Harry, Ouyang Ching, Dery Kenneth J, Le Keith, Longmate Jeffrey, Marek Claudia, St Amand R Paul, Krontiris Theodore G, Shively John E
Abstract excerpt
Fibromyalgia syndrome (FMS) is a chronic musculoskeletal pain disorder affecting 2% to 5% of the general population. Both genetic and environmental factors may be involved. To ascertain in an unbiased manner which genes play a role in the disorder, we performed complete exome sequencing on a subset of FMS patients. Out of 150 nuclear families (trios) DNA from 19 probands was subjected to complete exome...
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