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Article

Are Epigenetic Factors Implicated in Chronic Widespread Pain?

PloS one - 1 Jan 2016

Burri Andrea, Marinova Zoya, Robinson Mark D, Kühnel Brigitte, Waldenberger Melanie, Wahl Simone, Kunze Sonja, Gieger Christian, Livshits Gregory, Williams Frances

Abstract excerpt

BACKGROUND: Chronic widespread musculoskeletal pain (CWP) is the cardinal symptom of fibromyalgia and affects about 12% of the general population. Familial aggregation of CWP has been repeatedly demonstrated with estimated heritabilities of around 50%, indicating a genetic susceptibility. The objective of the study was to explore genome-wide disease-differentially methylated positions (DMPs) for chronic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27832094
DOI: 10.1371/journal.pone.0165548
PMCID: PMC5104434

Genes

HSPB6
MAOB
MDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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