Article
BLUF domain function does not require a metastable radical intermediate state.
Journal of the American Chemical Society - 26 Mar 2014
Lukacs Andras, Brust Richard, Haigney Allison, Laptenok Sergey P, Addison Kiri, Gil Agnieszka, Towrie Michael, Greetham Gregory M, Tonge Peter J, Meech Stephen R
Abstract excerpt
BLUF (blue light using flavin) domain proteins are an important family of blue light-sensing proteins which control a wide variety of functions in cells. The primary light-activated step in the BLUF domain is not yet established. A number of experimental and theoretical studies points to a role for photoinduced electron transfer (PET) between a highly conserved tyrosine and the flavin chromophore to form a...
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