Article
Brain-penetrating angiotensin-converting enzyme inhibitors and cognitive change in patients with dementia due to Alzheimer's disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2014
de Oliveira Fabricio Ferreira, Bertolucci Paulo Henrique Ferreira, Chen Elizabeth Suchi, Smith Marilia Cardoso
Abstract excerpt
Controversy over benefits of angiotensin-converting enzyme inhibitors (ACEIs) for treatment of dementia due to Alzheimer's disease (AD) led to this alternative investigational approach by the employment of pharmacogenetic methods, correlating the cognitive change of patients with late-onset AD with the presence of common ACE gene promoter polymorphisms, and stratifying the sample in groups of patients who...
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