Article
Bortezomib effect on E2F and cyclin family members in human hepatocellular carcinoma cell lines.
World journal of gastroenterology - 21 Jan 2014
Baiz Daniele, Dapas Barbara, Farra Rossella, Scaggiante Bruna, Pozzato Gabriele, Zanconati Fabrizio, Fiotti Nicola, Consoloni Lara, Chiaretti Sara, Grassi Gabriele
Abstract excerpt
AIM: To evaluate the effects of the proteasome inhibitor bortezomib (BZB) on E2Fs and related genes in hepatocellular carcinoma (HCC) cells. METHODS: The mRNA levels of the E2F family members (pro-proliferative: E2F1-3 and anti-proliferative: E2F4-8) and of their related genes cyclins and cyclin-...
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