Article
Primary open-angle glaucoma risk prediction with ABCA1 and LOC102723944 variants and their genotype-phenotype correlations in southern Chinese population.
Molecular genetics and genomics : MGG - 1 Nov 2023
Wu Zhenggen, Huang Chukai, Zheng Yuqian, Yuan Xiang-Ling, Chen Shaowan, Xu Yanxuan, Chen Li Jia, Pang Chi Pui, Zhang Mingzhi, Ng Tsz Kin
Abstract excerpt
Glaucoma is a leading cause of irreversible visual impairment and blindness worldwide. Previous genome-wide association studies have identified caveolin-1 (CAV1), ATP-binding cassette A1 (ABCA1), and forkhead box C1 (FOXC1) loci associated with primary open angle glaucoma (POAG), a major subtype of glaucoma. This study aimed to fine map the association pattern of FOXC1 locus with POAG and determine the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.