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Article

Genetic variation on the BAT1-NFKBIL1-LTA region of major histocompatibility complex class III associates with periodontitis.

Infection and immunity - 1 May 2014

Kallio K A Elisa, Marchesani Marja, Vlachopoulou Efthymia, Mäntylä Päivi, Paju Susanna, Buhlin Kåre, Suominen Anna L, Contreras Johanna, Knuuttila Matti, Hernandez Marcela, Huumonen Sisko, Nieminen Markku S, Perola Markus, Sinisalo Juha, Lokki Marja-Liisa, Pussinen Pirkko J

Abstract excerpt

Periodontitis is a chronic inflammatory disease with a multifactorial etiology. We investigated whether human major histocompatibility complex (MHC) polymorphisms (6p21.3) are associated with periodontal parameters. Parogene 1 population samples (n = 169) were analyzed with 13,245 single nucleotide polymorphisms (SNPs) of the MHC region. Eighteen selected SNPs (P ≤ 0.001) were replicated in Parogene 2 population...

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Source

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Identifiers

PMID: 24566624
DOI: 10.1128/IAI.01681-13
PMCID: PMC3993418

Genes

LTA
NFKBIL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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