Article
Salivary biomarkers in association with periodontal parameters and the periodontitis risk haplotype.
Innate immunity - 1 Oct 2018
Liukkonen Joonas, Gürsoy Ulvi K, Könönen Eija, Gürsoy Mervi, Metso Jari, Salminen Aino, Kopra Elisa, Jauhiainen Matti, Mäntylä Päivi, Buhlin Kåre, Paju Susanna, Sorsa Timo, Nieminen Markku S, Lokki Marja-Liisa, Sinisalo Juha, Pussinen Pirkko J
Abstract excerpt
Genetic factors play a role in periodontitis. Here we examined whether the risk haplotype of MHC class III region BAT1-NFKBIL1-LTA and lymphotoxin-α polymorphisms associate with salivary biomarkers of periodontal disease. A total of 455 individuals with detailed clinical and radiographic periodontal health data were included in the study. A 610 K genotyping chip and a Sequenom platform were used in genotyping...
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