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Article

Correlation between methyltetrahydrofolate reductase (MTHFR) polymorphisms and isolated patent ductus arteriosus in Taiwan.

Heart, lung & circulation - 1 Jul 2014

Chao Chia-Sheng, Wei Jeng, Huang Hurng-Wern, Yang Shyh-Chyun

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C gene polymorphisms are associated with the risk of patent ductus arteriosus (PDA) congenital heart defects. This study aimed to determine the association of these polymorphisms in patients with isolated PDA and in non-PDA patients group without congenital heart disease. METHODS: This retrospective case-controlled study was undertaken in 17...

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Source

Identifiers

PMID: 24566197
DOI: 10.1016/j.hlc.2014.01.010

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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