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Article

Genetics of the patent ductus arteriosus (PDA) and pharmacogenetics of PDA treatment.

Seminars in fetal & neonatal medicine - 1 Aug 2018

Lewis Tamorah R, Shelton Elaine L, Van Driest Sara L, Kannankeril Prince J, Reese Jeff

Abstract excerpt

Patent ductus arteriosus (PDA) is a frequent, complex, and difficult to treat clinical syndrome among preterm infants in the neonatal intensive care unit. In addition to known clinical risk factors, there are emerging data about genetic predisposition to PDA in both animal and human models. Clinical response and toxicity from drugs used to treat PDA are highly variable. Developmental and genetic aspects of...

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Identifiers

PMID: 29510900
DOI: 10.1016/j.siny.2018.02.006
PMCID: PMC6098727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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