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Article

Prioritizing protein complexes implicated in human diseases by network optimization.

BMC systems biology - 1 Jan 2014

Chen Yong, Jacquemin Thibault, Zhang Shuyan, Jiang Rui

Abstract excerpt

BACKGROUND: The detection of associations between protein complexes and human inherited diseases is of great importance in understanding mechanisms of diseases. Dysfunctions of a protein complex are usually defined by its member disturbance and consequently result in certain diseases. Although individual disease proteins have been widely predicted, computational methods are still absent for systematically...

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Identifiers

PMID: 24565064
DOI: 10.1186/1752-0509-8-S1-S2
PMCID: PMC4080363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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