Article
Simultaneous inferences based on empirical Bayes methods and false discovery rates ineQTL data analysis.
BMC genomics - 1 Jan 2013
Chakraborty Arindom, Jiang Guanglong, Boustani Malaz, Liu Yunlong, Skaar Todd, Li Lang
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have identified hundreds of genetic variants associated with complex human diseases, clinical conditions and traits. Genetic mapping of expression quantitative trait loci (eQTLs) is providing us with novel functional effects of thousands of single nucleotide polymorphisms (SNPs). In a classical quantitative trail loci (QTL) mapping problem multiple tests are done...
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