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Article

Estimation and selection in high-dimensional genomic studies for developing molecular diagnostics.

Biostatistics (Oxford, England) - 1 Apr 2011

Matsui Shigeyuki, Noma Hisashi

Abstract excerpt

In the development of molecular diagnostics, the main objective in high-dimensional genomic studies such as DNA microarray studies is to screen out genes strongly associated with clinical phenotypes to significantly improve diagnostic capabilities. The basic statistical task is thus estimation of the strengths of association or effect sizes for individual genes. We develop an empirical Bayes estimation method...

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PMID: 20841334
DOI: 10.1093/biostatistics/kxq057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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