Article
Mature Epitope Density--a strategy for target selection based on immunoinformatics and exported prokaryotic proteins.
BMC genomics - 1 Jan 2013
Santos Anderson R, Pereira Vanessa Bastos, Barbosa Eudes, Baumbach Jan, Pauling Josch, Röttger Richard, Turk Meritxell Zurita, Silva Artur, Miyoshi Anderson, Azevedo Vasco
Abstract excerpt
BACKGROUND: Current immunological bioinformatic approaches focus on the prediction of allele-specific epitopes capable of triggering immunogenic activity. The prediction of major histocompatibility complex (MHC) class I epitopes is well studied, and various software solutions exist for this purpose. However, currently available tools do not account for the concentration of epitope products in the mature protein...
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