Article
Basal subtype, as approximated by triple-negative phenotype, is associated with locoregional recurrence in a case-control study of women with 0-3 positive lymph nodes after mastectomy.
Annals of surgical oncology - 1 Jun 2014
Khan A J, Milgrom S A, Barnard N, Higgins S A, Moran M, Shahzad Haseeba, Kim S, Goyal S, Al-Faraj F, Kirstein L, Kearney T, Haffty B G
Abstract excerpt
PURPOSE: Basal subtype, as approximated by the triple-negative phenotype (ER-PR-Her2-), has correlated with higher LRR in recent studies. Indications for postmastectomy RT (PMRT) in women with 0-3 positive lymph nodes remain unclear. We evaluated the importance of biologic subtype in a cohort of women with LRR after mastectomy. METHODS: We identified 22 women with 0-3 positive lymph nodes at our institution who...
Topics
- Antineoplastic Agents
- Biomarkers, Tumor
- Case-Control Studies
- Female
- Humans
- Lymphatic Metastasis
- Mastectomy
- Neoplasm Recurrence, Local
- Phenotype
- Receptor, ErbB-2
- Receptors, Estrogen
- Receptors, Progesterone