Article
Prognostic value of basal phenotype in HER2-overexpressing breast cancer.
Annals of surgical oncology - 1 Mar 2012
Bagaria Sanjay P, Ray Partha S, Wang Jinhua, Kropcho Luisa, Chung Alice, Sim Myung-Shin, Shamonki Jaime M, Martino Silvana, Cui Xiaojiang, Giuliano Armando E
Abstract excerpt
BACKGROUND: Primary breast cancers that overexpress human epidermal growth factor receptor 2 have variable biological features and clinical outcomes. A subgroup of HER2-overexpressing tumors that express basal-like immunohistochemical markers-the so-called basal-HER2+ subtype--is associated with poor prognosis. We investigated the clinical relevance of this basal-HER2+ subtype within HER2-overexpressing breast...
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