Article
Prognostic value of basal phenotype in HER2-overexpressing breast cancer.
Annals of surgical oncology - 1 Mar 2012
Bagaria Sanjay P, Ray Partha S, Wang Jinhua, Kropcho Luisa, Chung Alice, Sim Myung-Shin, Shamonki Jaime M, Martino Silvana, Cui Xiaojiang, Giuliano Armando E
Abstract excerpt
BACKGROUND: Primary breast cancers that overexpress human epidermal growth factor receptor 2 have variable biological features and clinical outcomes. A subgroup of HER2-overexpressing tumors that express basal-like immunohistochemical markers-the so-called basal-HER2+ subtype--is associated with...
Topics
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Female
- Humans
- Immunohistochemistry
- Keratins
- Middle Aged
- Phenotype
- Prognosis
- Proportional Hazards Models
- Receptor, ErbB-2
- Receptors, Estrogen
- Survival Rate