Article
How basal are triple-negative breast cancers?
International journal of cancer - 1 Jul 2008
Bertucci François, Finetti Pascal, Cervera Nathalie, Esterni Benjamin, Hermitte Fabienne, Viens Patrice, Birnbaum Daniel
Abstract excerpt
The basal molecular subtype of breast cancer (BC) is defined by the mRNA expression pattern of an intrinsic approximately 500-gene set. It is the most homogeneous subtype in transcriptional terms, and one of the most aggressive in prognostic terms. Clinical trials testing new systemic therapeutic strategies have been launched in basal BCs. Although no proof of evidence has yet been reported, basal tumors are...
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