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Article

Hugin+ neurons provide a link between sleep homeostat and circadian clock neurons.

Proceedings of the National Academy of Sciences of the United States of America - 23 Nov 2021

Schwarz Jessica E, King Anna N, Hsu Cynthia T, Barber Annika F, Sehgal Amita

Abstract excerpt

Sleep is controlled by homeostatic mechanisms, which drive sleep after wakefulness, and a circadian clock, which confers the 24-h rhythm of sleep. These processes interact with each other to control the timing of sleep in a daily cycle as well as following sleep deprivation. However, the mechanisms by which they interact are poorly understood. We show here that hugin+ neurons, previously identified as neurons...

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Identifiers

PMID: 34782479
DOI: 10.1073/pnas.2111183118
PMCID: PMC8617458

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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