Article
A genome-wide association study demonstrates significant genetic variation for fracture risk in Thoroughbred racehorses.
BMC genomics - 21 Feb 2014
Blott Sarah C, Swinburne June E, Sibbons Charlene, Fox-Clipsham Laura Y, Helwegen Maud, Hillyer Lynn, Parkin Tim D H, Newton J Richard, Vaudin Mark
Abstract excerpt
BACKGROUND: Thoroughbred racehorses are subject to non-traumatic distal limb bone fractures that occur during racing and exercise. Susceptibility to fracture may be due to underlying disturbances in bone metabolism which have a genetic cause. Fracture risk has been shown to be heritable in several species but this study is the first genetic analysis of fracture risk in the horse. RESULTS: Fracture cases (n = 269)...
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