Article
Identification and validation of risk loci for osteochondrosis in standardbreds.
BMC genomics - 12 Jan 2016
McCoy Annette M, Beeson Samantha K, Splan Rebecca K, Lykkjen Sigrid, Ralston Sarah L, Mickelson James R, McCue Molly E
Abstract excerpt
BACKGROUND: Osteochondrosis (OC), simply defined as a failure of endochondral ossification, is a complex disease with both genetic and environmental risk factors that is commonly diagnosed in young horses, as well as other domestic species. Although up to 50 % of the risk for developing OC is reportedly inherited, specific genes and alleles underlying risk are thus far completely unknown. Regions of the genome...
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