Article
Inbreeding depression and the probability of racing in the Thoroughbred horse.
Proceedings. Biological sciences - 29 Jun 2022
Hill Emmeline W, Stoffel Martin A, McGivney Beatrice A, MacHugh David E, Pemberton Josephine M
Abstract excerpt
Small effective population sizes and active inbreeding can lead to inbreeding depression due to deleterious recessive mutations exposed in the homozygous state. The Thoroughbred racehorse has low levels of population genetic diversity, but the effects of genomic inbreeding in the population are unknown. Here, we quantified inbreeding based on runs of homozygosity (ROH) using 297 K SNP genotypes from 6128 horses...
Topics
- Animals
- Genome-Wide Association Study
- Horses
- Inbreeding
- Inbreeding Depression
- Polymorphism, Single Nucleotide
- Probability