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Article

Autophagy in immunity

5 Sept 2012

Abstract excerpt

Autophagy is now emerging as a spotlight in trafficking events that activate innate and adaptive immunity. It facilitates innate pathogen detection and antigen presentation, as well as pathogen clearance and lymphocyte homeostasis. In this review, we first summarize new insights into its functions in immunity, which underlie its associations with autoimmunity. As some lines of evidence are emerging to support its...

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PMID: 22878595
DOI: 10.4161/auto.21212

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