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Article

TNF-α promoter polymorphisms and risk of recurrence in patients with squamous cell carcinomas of the nonoropharynx.

International journal of cancer - 1 Oct 2014

Zhang Caiyun, Sturgis Erich M, Zheng Hongliang, Zafereo Mark E, Wei Qingyi, Li Guojun

Abstract excerpt

Functional polymorphisms of tumor necrosis factor-alpha (TNF-α) may play a critical role in the regulation of immune and inflammatory responses and could affect transcriptional levels of the TNF-α gene and thus contribute to carcinogenesis and outcomes of cancer patients. In a cohort study, we explored the associations between TNF-α polymorphisms and risk of recurrence of squamous cell carcinoma of the...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Head and Neck Neoplasms

Share to Neoplasm Recurrence, Local

Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 24550071
DOI: 10.1002/ijc.28793
PMCID: PMC4107187

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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