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Type II grass carp reovirus utilizes autophagosomes for viroplasm formation and subclinical persistent infection

4 Apr 2025

Abstract excerpt

. GCRV is categorized into three genotypes, with type II (GCRV-II) being the predominant strain circulating in China. Reoviruses are known to replicate and assemble in cytoplasmic inclusion bodies termed viroplasms; however, information regarding the formation of GCRV-II viroplasms and their specific roles in virus infection remains largely unknown. In this study, we investigated the formation and characteristics...

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PMID: 40172227
DOI: 10.1128/jvi.00352-25

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