Article
Identification of the Staphylococcus aureus vfrAB operon, a novel virulence factor regulatory locus.
Infection and immunity - 1 May 2014
Bose Jeffrey L, Daly Seth M, Hall Pamela R, Bayles Kenneth W
Abstract excerpt
During a screen of the Nebraska Transposon Mutant Library, we identified 71 mutations in the Staphylococcus aureus genome that altered hemolysis on blood agar medium. Although many of these mutations disrupted genes known to affect the production of alpha-hemolysin, two of them were associated with an apparent operon, designated vfrAB, that had not been characterized previously. Interestingly, a ΔvfrB mutant...
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